Stensbøl, T: search on Z-Library

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1

The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT 3 receptor expressing interneurons: An in vitro study in rat hippocampus slices

Dale, Elena, Grunnet, Morten, Pehrson, Alan L., Frederiksen, Kristen, Larsen, Peter H., Nielsen, Jacob, Stensbøl, Tine B., Ebert, Bjarke, Yin, Haolan, Lu, Dunguo, Liu, Huiquing, Jensen, Thomas N., Yan

Journal:

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

2

New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III

Huynh, Tri H. V., Erichsen, Mette N., Tora, Amélie S., Goudet, Cyril, Sagot, Emmanuelle, Assaf, Zeinab, Thomsen, Christian, Brodbeck, Robb, Stensbøl, Tine B., Bjørn-Yoshimoto, Walden E., Nielsen, Birg

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.50 MB

english, 2016

3

( S )-Homo-AMPA, a Specific Agonist at the mGlu 6 Subtype of Metabotropic Glutamic Acid Receptors

Ahmadian, Haleh, Nielsen, Birgitte, Bräuner-Osborne, Hans, Johansen, Tommy N., Stensbøl, Tine B., Sløk, Frank A., Sekiyama, Naohiro, Nakanishi, Shigetada, Krogsgaard-Larsen, Povl, Madsen, Ulf

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 161 KB

english, 1997

4

Design, Synthesis, and Pharmacological Characterization of Novel, Potent NMDA Receptor Antagonists

Conti, Paola, De Amici, Marco, Grazioso, Giovanni, Roda, Gabriella, Barberis Negra, Federico F., Nielsen, Birgitte, Stensbøl, Tine B., Madsen, Ulf, Bräuner-Osborne, Hans, Frydenvang, Karla, De Sarro,

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

5

Novel Class of Potent 4-Arylalkyl Substituted 3-Isoxazolol GABA A Antagonists: Synthesis, Pharmacology, and Molecular Modeling

Frølund, Bente, Jørgensen, Anne T., Tagmose, Lena, Stensbøl, Tine B., Vestergaard, Henrik T., Engblom, Christine, Kristiansen, Uffe, Sanchez, Connie, Krogsgaard-Larsen, Povl, Liljefors, Tommy

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 267 KB

english, 2002

6

C.02.03 Developing D2 partial agonists to optimise augmentation therapy in MDD

Journal:

European Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 65 KB

english, 2015

7

Analogues of Carbacholine: Synthesis and Relationship between Structure and Affinity for Muscarinic and Nicotinic Acetylcholine Receptors

Birgitte Søkilde, Ivan Mikkelsen, Tine B. Stensbøl, Birgit Andersen, Søren Ebdrup, Povl Krogsgaard-Larsen, Erik Falch

Journal:

Archiv der Pharmazie

Year:

1996

Language:

english

File:

PDF, 846 KB

english, 1996

8

Associating in vitro target binding and in vivo CNS occupancy of serotonin reuptake inhibitors in rats: The role of free drug concentrations

Bundgaard, Christoffer, Sveigaard, Christina, Brennum, Lise T., Stensbøl, Tine B.

Journal:

Year:

2012

Language:

english

File:

PDF, 702 KB

english, 2012

9

Design of novel conformationally restricted analogues of glutamic acid

Paola Conti, Marco De Amici, Gabriella Roda, Giulio Vistoli, Tine Bryan Stensbøl, Hans Bräuner-Osborne, Ulf Madsen, Lucio Toma, Carlo De Micheli

Journal:

Year:

2003

Language:

english

File:

PDF, 373 KB

english, 2003

10

Design and synthesis of a new series of 4-alkylated 3-isoxazolol GABAA antagonists

Bente Frølund, Lena Tagmose, Anne T. Jørgensen, Uffe Kristiansen, Tine B. Stensbøl, Tommy Liljefors, Povl Krogsgaard-Larsen

Journal:

European Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 352 KB

english, 2003

11

Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist

Ulf Madsen, Frank A Sløk, Tine B Stensbøl, Hans Bräuner-Osborne, Hans-Christian H Lützhøft, Miguel V Poulsen, Lisbeth Eriksen, Povl Krogsgaard-Larsen

Journal:

European Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

12

2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

Tommy N. Johansen, Yves L. Janin, Birgitte Nielsen, Karla Frydenvang, Hans Bräuner-Osborne, Tine B. Stensbøl, Stine B. Vogensen, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

13

S. 19.04 Speeding up drug development: results of a public private partnership

Stensbol, T.B., Kapur, S. Shitij

Journal:

European Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 58 KB

english, 2015

14

Brexpiprazole I: In Vitro and In Vivo Characterization of a Novel Serotonin-Dopamine Activity Modulator

Maeda, K., Sugino, H., Akazawa, H., Amada, N., Shimada, J., Futamura, T., Yamashita, H., Ito, N., McQuade, R. D., Mork, A., Pehrson, A. L., Hentzer, M., Nielsen, V., Bundgaard, C., Arnt, J., Stensbol,

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2014

Language:

english

File:

PDF, 475 KB

english, 2014

15

Assessing the Cognitive Translational Potential of a Mouse Model of the 22q11.2 Microdeletion Syndrome

Nilsson, Simon RO., Fejgin, Kim, Gastambide, Francois, Vogt, Miriam A., Kent, Brianne A., Nielsen, Vibeke, Nielsen, Jacob, Gass, Peter, Robbins, Trevor W., Saksida, Lisa M., Stensbøl, Tine B., Trickle

Journal:

Cerebral Cortex

Year:

2016

Language:

english

File:

PDF, 681 KB

english, 2016

16

Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist

Stine B. Vogensen, Henrik S. Jensen, Tine B. Stensbøl, Karla Frydenvang, Benny Bang-Andersen, Tommy N. Johansen, Jan Egebjerg, Povl Krogsgaard-Larsen

Journal:

Year:

2000

Language:

english

File:

PDF, 363 KB

english, 2000

17

Piperidinyl-3-phosphinic acids as novel uptake inhibitors of the neurotransmitter γ-aminobutyric acid (GABA)

Jan Kehler, Tine B. Stensbøl, Povl Krogsgaard-Larsen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

18

Synthesis and Resolution of ATPO, a Potent and Selective Ampa Receptor Antagonist

Møller, Eva H., Brehm, Lotte, Johansen, Tommy N., Stensbøl, Tine B., Krogsgaard-larsen, Povl

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1999

Language:

english

File:

PDF, 76 KB

english, 1999

19

NEWMEDS special issue commentary

Stensbøl, Tine Bryan, Kapur, Shitij

Journal:

Psychopharmacology

Year:

2015

Language:

english

File:

PDF, 201 KB

english, 2015

20

Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1–4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

Eva H. Møller, Jan Egebjerg, Lotte Brehm, Tine B. Stensbøl, Tommy N. Johansen, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

1999

Language:

english

File:

PDF, 702 KB

english, 1999

21

Differential effects of γ-secretase and BACE1 inhibition on brain Aβ levels in vitro and in vivo

Anders Brandt Elvang, Christiane Volbracht, Lars Østergaard Pedersen, Klaus Gjervig Jensen, Jens-Jakob Karlsson, Stine Anna Larsen, Arne Mørk, Tine Bryan Stensbøl, Jesper Frank Bastlund

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 435 KB

english, 2009

22

Characterization of a new AMPA receptor radioligand, [3H]2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid

Tine B Stensbøl, Frank A Sløk, Joseph Trometer, Stephen Hurt, Bjarke Ebert, Connie Kjøller, Jan Egebjerg, Ulf Madsen, Nils H Diemer, Povl Krogsgaard-Larsen

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 1.02 MB

english, 1999

23

[3H]ATPA: a high affinity ligand for GluR5 kainate receptors

Ken Hoo, Beatta Legutko, Geihan Rizkalla, Michele Deverill, C.R Hawes, Gareth J Ellis, Tine B Stensbol, Povl Krogsgaard-Larsen, Phil Skolnick, David Bleakman

Journal:

Neuropharmacology

Year:

1999

Language:

english

File:

PDF, 143 KB

english, 1999

24

Design of Cyclopentaisoxazoline Amino Acids as Conformationally Constrained Agonists at Glutamate Receptors

Paola Conti, Marco De Amici, Giovanni Grazioso, Gabriella Roda, Tine B. Stensbøl, Hans Bräuner-Osborne, Ulf Madsen, Lucio Toma, Carlo De Micheli

Journal:

European Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 165 KB

english, 2003

25

Synthesis and receptor binding affinity of new selective GluR5 ligands

Lennart Bunch, Tina H. Johansen, Hans Bräuner-Osborne, Tine B. Stensbøl, Tommy N. Johansen, Povl Krogsgaard-Larsen, Ulf Madsen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 151 KB

english, 2001

26

Synthesis and Anticonvulsant Activity of Novel Bicyclic Acidic Amino Acids

Conti, Paola, De Amici, Marco, Joppolo di Ventimiglia, Samuele, Stensbøl, Tine B., Madsen, Ulf, Bräuner-Osborne, Hans, Russo, Emilio, De Sarro, Giovambattista, Bruno, Giuseppe, Micheli, Carlo De

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

27

Design, Synthesis, and Pharmacological Characterization of N - and O -Substituted 5,6,7,8-Tetrahydro-4 H -isoxazolo[4,5- d ]azepin-3-ol Analogues: Novel 5-HT 2A /5-HT 2C Receptor Agonists with Pro-Cognitive Properties

Jensen, Anders A., Plath, Niels, Pedersen, Martin H. F., Isberg, Vignir, Krall, Jacob, Wellendorph, Petrine, Stensbøl, Tine B., Gloriam, David E., Krogsgaard-Larsen, Povl, Frølund, Bente

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 3.34 MB

english, 2013

28

Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist

Tine B. Stensbøl, Henrik S. Jensen, Birgitte Nielsen, Tommy N. Johansen, Jan Egebjerg, Karla Frydenvang, Povl Krogsgaard-Larsen

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 373 KB

english, 2001

29

Brexpiprazole II: Antipsychotic-Like and Procognitive Effects of a Novel Serotonin-Dopamine Activity Modulator

Maeda, K., Lerdrup, L., Sugino, H., Akazawa, H., Amada, N., McQuade, R. D., Stensbol, T. B., Bundgaard, C., Arnt, J., Kikuchi, T.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2014

Language:

english

File:

PDF, 537 KB

english, 2014

30

An acetylcholine alpha7 positive allosteric modulator rescues a schizophrenia-associated brain endophenotype in the 15q13.3 microdeletion, encompassing CHRNA7

Gass, Natalia, Weber-Fahr, Wolfgang, Sartorius, Alexander, Becker, Robert, Didriksen, Michael, Stensbøl, Tine Bryan, Bastlund, Jesper Frank, Meyer-Lindenberg, Andreas, Schwarz, Adam J.

Journal:

European Neuropsychopharmacology

Year:

2016

Language:

english

File:

PDF, 1.44 MB

english, 2016

31

Synthesis of enantiomerically pure milnacipran analogs and inhibition of dopamine, serotonin, and norepinephrine transporters

Heidi Roggen, Jan Kehler, Tine Bryan Stensbøl, Tore Hansen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 137 KB

english, 2007

32

Discovery of 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): A Novel Multimodal Compound for the Treatment of Major Depressive Disorder

Bang-Andersen, Benny, Ruhland, Thomas, Jørgensen, Morten, Smith, Garrick, Frederiksen, Kristen, Jensen, Klaus Gjervig, Zhong, Huailing, Nielsen, Søren Møller, Hogg, Sandra, Mørk, Arne, Stensbøl, Tine

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

33

Potent 4-Aryl- or 4-Arylalkyl-Substituted 3-Isoxazolol GABAA Antagonists: Synthesis, Pharmacology, and Molecular Modeling

Frølund, Bente, Jensen, Lars S., Guandalini, Luca, Canillo, Carolina, Vestergaard, Henrik T., Kristiansen, Uffe, Nielsen, Birgitte, Stensbøl, Tine B., Madsen, Christian, Krogsgaard-Larsen, Povl

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 365 KB

english, 2005

34

P.2.b.015 Lu AA21004: a novel potential treatment for mood disorders

N. Moore, B. Bang-Andersen, L. Brennum, K. Fredriksen, S. Hogg, A. Mork, T. Stensbol, H. Zhong, C. Sanchez, D. Smith

Journal:

European Neuropsychopharmacology

Year:

2008

Language:

english

File:

PDF, 60 KB

english, 2008

35

Synthesis and Pharmacology of a New AMPA−Kainate Receptor Agonist with Potent Convulsant Activity

Conti, Paola, De Amici, Marco, De Sarro, Giovambattista, Stensbøl, Tine Bryan, Bräuner-Osborne, Hans, Madsen, Ulf, De Micheli, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 50 KB

english, 1998

36

Three-Dimensional Structure of the Ligand-Binding Core of GluR2 in Complex with the Agonist ( S ) - ATPA: Implications for Receptor Subunit Selectivity

Lunn, Marie-Louise, Hogner, Anders, Stensbøl, Tine B., Gouaux, Eric, Egebjerg, Jan, Kastrup, Jette S.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 156 KB

english, 2003

37

Chemo-Enzymatic Synthesis of (2 S ,4 R )-2-Amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic Acid: A Novel Selective Inhibitor of Human Excitatory Amino Acid Transporter Subtype 2

Sagot, Emanuelle, Jensen, Anders A., Pickering, Darryl S., Pu, Xiaosui, Umberti, Michelle, Stensbøl, Tine B., Nielsen, Birgitte, Assaf, Zeinab, Aboab, Bétina, Bolte, Jean, Gefflaut, Thierry, Bunch, L

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 320 KB

english, 2008

38

Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA

Tommy N. Johansen, Tine B. Stensbøl, Birgitte Nielsen, Stine B. Vogensen, Karla Frydenvang, Frank A. Sløk, Hans Brünum, uner-Osborne, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

2001

Language:

english

File:

PDF, 511 KB

english, 2001

39

Aryl and cycloalkyl analogues of AMPA: synthetic, pharmacological and stereochemical aspects

Niels Skjærbæk, Lotte Brehm, Tommy N. Johansen, Lene M. Hansen, Birgitte Nielsen, Bjarke Ebert, Karina K. Søby, Tine B. Stensbøl, Erik Falch, Povl Krogsgaard-Larsen

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 1.32 MB

english, 1998

40

Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors

Mette B. Hermit, Jeremy R. Greenwood, Birgitte Nielsen, Lennart Bunch, Charlotte G. Jørgensen, Henrik T. Vestergaard, Tine B. Stensbøl, Connie Sanchez, Povl Krogsgaard-Larsen, Ulf Madsen, Hans Bräuner

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 414 KB

english, 2004

41

4-Aryl-5-(4-Piperidyl)-3-Isoxazolol GABA A Antagonists: Synthesis, Pharmacology, and Structure−Activity Relationships

Frølund, Bente, Jensen, Lars S., Storustovu, Signe I., Stensbøl, Tine B., Ebert, Bjarke, Kehler, Jan, Krogsgaard-Larsen, Povl, Liljefors, Tommy

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 81 KB

english, 2007

42

( S )-2-Amino-3-(3-hydroxy-7,8-dihydro-6 H -cyclohepta[ d ]isoxazol-4-yl)propionic Acid, a Potent and Selective Agonist at the GluR5 Subtype of Ionotropic Glutamate Receptors. Synthesis, Modeling, and Molecular Pharmacology

Brehm, Lotte, Greenwood, Jeremy R., Hansen, Kasper B., Nielsen, Birgitte, Egebjerg, Jan, Stensbøl, Tine B., Bräuner-Osborne, Hans, Sløk, Frank A., Kronborg, Tine T. A., Krogsgaard-Larsen, Povl

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 297 KB

english, 2003

43

Chemo-Enzymatic Synthesis of a Series of 2,4- Syn -Functionalized ( S )-Glutamate Analogues: New Insight into the Structure−Activity Relation of Ionotropic Glutamate Receptor Subtypes 5, 6, and 7

Sagot, Emanuelle, Pickering, Darryl S., Pu, Xiaosui, Umberti, Michelle, Stensbøl, Tine B., Nielsen, Birgitte, Chapelet, Marion, Bolte, Jean, Gefflaut, Thierry, Bunch, Lennart

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 877 KB

english, 2008

44

Synthesis and Enantiopharmacology of New AMPA-Kainate Receptor Agonists

Conti, Paola, De Amici, Marco, De Sarro, Giovambattista, Rizzo, Milena, Stensbøl, Tine Bryan, Bräuner-Osborne, Hans, Madsen, Ulf, Toma, Lucio, De Micheli, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 154 KB

english, 1999

45

Heteroaryl Analogues of AMPA. 2. Synthesis, Absolute Stereochemistry, Photochemistry, and Structure−Activity Relationships

Falch, Erik, Brehm, Lotte, Mikkelsen, Ivan, Johansen, Tommy N., Skjærbæk, Niels, Nielsen, Birgitte, Stensbøl, Tine B., Ebert, Bjarke, Krogsgaard-Larsen, Povl

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 291 KB

english, 1998

46

A mouse model of the 15q13.3 microdeletion syndrome shows prefrontal neurophysiological dysfunctions and attentional impairment

Nilsson, Simon R. O., Celada, Pau, Fejgin, Kim, Thelin, Jonas, Nielsen, Jacob, Santana, Noemí, Heath, Christopher J., Larsen, Peter H., Nielsen, Vibeke, Kent, Brianne A., Saksida, Lisa M., Stensbøl, T

Journal:

Psychopharmacology

Year:

2016

Language:

english

File:

PDF, 782 KB

english, 2016

47

P.2.d.006 The novel antidepressant Lu AA21004 exerts its multi-modal activity through serotonergic targets

C. Sanchez, S.M. Nielsen, A. Pehrson, H. Zhong, A.B. Lassen, S. Bisulco, A. Mørk, G. Wegener, T.B. Stensbøl

Journal:

European Neuropsychopharmacology

Year:

2011

Language:

english

File:

PDF, 72 KB

english, 2011

48

Novel 1-Hydroxyazole Bioisosteres of Glutamic Acid. Synthesis, Protolytic Properties, and Pharmacology

Stensbøl, Tine B., Uhlmann, Peter, Morel, Sandrine, Eriksen, Birgitte L., Felding, Jakob, Kromann, Hasse, Hermit, Mette B., Greenwood, Jeremy R., Braüner-Osborne, Hans, Madsen, Ulf, Junager, Finn, Kro

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 253 KB

english, 2002

49

Synthesis and Pharmacology of 3-Isoxazolol Amino Acids as Selective Antagonists at Group I Metabotropic Glutamic Acid Receptors

Madsen, Ulf, Bräuner-Osborne, Hans, Frydenvang, Karla, Hvene, Lise, Johansen, Tommy N., Nielsen, Birgitte, Sánchez, Connie, Stensbøl, Tine B., Bischoff, Francois, Krogsgaard-Larsen, Povl

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 173 KB

english, 2001

50

Changes in KCNQ2 immunoreactivity in the amygdala in two rat models of temporal lobe epilepsy

Silke Penschuck, Jesper F. Bastlund, Henrik Sindal Jensen, Tine Bryan Stensbol, Jan Egebjerg, William P. Watson

Journal:

Molecular Brain Research

Year:

2005

Language:

english

File:

PDF, 343 KB

english, 2005

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